Executive Summary Memo for Market Analysis of Parkinson's Disease Research Paper

Executive Summary Memo for Market Analysis of Parkinson's Disease - Research Paper Example The exact cause of such effects is not known, although aggressive research in this area is underway. Irrespective of the cause, a patient with full-blown Parkinson’s disease will have four cardinal symptoms, tremor at rest, bradykinesia, rigidity, and difficulties with balance. Such patients due to difficulty in movement control are virtually rendered nonfunctional, and the quality of their life is severely affected (1). From the market point of view, thus there is huge untapped potential in the Parkinsons disease therapy market. The exact cause of the disease is not known, but a considerable number of individuals suffer from this problem. The medical therapy assumes a central role in the management plan, and therefore a variety of medications are available for symptomatic treatment. Despite new research to discover newer drugs, there is no medication as yet which has shown promise in arresting the pathological process of the Parkinsons disease. Therefore, this existing gap can create opportunities newer modalities of therapies, therapeutic agents, or curative agents (1). The Worldwide market of Parkinson’s disease is huge, since it is a common neurological disease with a disease burden of 4.1m affected individual. It is expected that its prevalence will rise in the coming years with increased clinical interventions in different forms. Current treatments or therapeutic choices are unsatisfactory making the unmet needs of this market a huge one, creating significant market opportunity. Although the market is global, in developed world, almost all counties constitute the major markets of such drugs. These countries are USA, Japan, France, Italy, Germany, Spain, and the UK. Compared to last evaluation of 2006 the market has been predicted to grow beyond $4.6bn from its base of $2.2bn, which interestingly was 11% larger than its base of 2005. The market is expected to increase in an exponential rate due to the fact that

Primary criticisms of American Cinema and Griffith's montage by Sergei Assignment

Primary criticisms of American Cinema and Griffith's montage by Sergei Eisenstein - Assignment Example At the core of their opinions, the ideas have come out of different philosophies asserting the importance of arts and esthetic medium to provide education or entertainment to people. In later age, as the American cinema was highly influenced with its industrial structure American Cinema tended more and more towards the entertainment which could provide good returns of investment in filmmaking. On the other hand, Russian cinema had devoted much to the ideas which regarding cinema as a medium of awareness and provoking. Due to such difference of opinions, Sergei Eisenstein, who was most profound of early Russian filmmakers had critiqued some of the concepts developed and defined by D.W. Griffith. One very important part of that criticism was Eisenstein’s criticism of Griffith’s theory of montage. In the modern day theory of montage Sergei Eisenstein’s assumption for montage are widely accepted for providing a ground for cinematic understanding for fast cutting and expression through montages. As followers to Griffith’s theories Sergei Eisenstein had developed Montage theory according to his philosophical set back based in Hegel and Marx. Although, developed over Griffithian grammar, Eisenstein’s theory to montage shows some contrasting difference as well. Utilization of montages in Griffithian Cinema In a modern day scenario, the term montage briefly suggest a number of small sized shots arranged in a manner to express a particular part of story or an effect. The montages are quite common is almost all the movies made nowadays. Depending on its use and requirement montage may be musical, action packed, blurred or deluding. A profound example of modern montages include David Fincher’s ‘Fight Club’ (Pitt 1999) using a sequence of shots expressing protagonist Jack’s nausea from its surrounding and further his remembrance of his own past that he had been unaware of. Another example contains Martin Scorsese’s depiction of police training in ‘The Departed’ (Nicholson 2006). D.W. Griffith’s earlier movies are supposed to set the basic grammar of cinema. There are number of occasions when Griffith has used sequencing shots without a direct connectivity of moment. Griffith’s montages were involved in compressing the happening of an event. However, without giving much for dialectical montages or other philosophical esthetical presentations, Griffith had designs the base for montage which could already establish montage as a different and particular approach to cinematic timeline. Anyways, the conceptualization and development of those theories is due to Sergei Einstein. How Eisenstein could identify power of Griffithian montage and could be motivated to enhance his own montage theory comes out in his quote I can’t recall who speaks with whom in one of the street scenes of the modern story of Intolerance. But I shall never forget the mask of the passer-by with nose pointed forward between spectacles and straggly beard, walking with hands behind his back as if he were manacled. As he passes he interrupts the most pathetic moment in the conversation of the suffering boy and girl. I can remember next to nothing of the couple, but